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Acestea sunt clasificate în grupuri cu risc scăzut şi grupuri cu risc înalt, în funcţie de potenţialul oncogenic. Cunoscându-se potenţialul oncogenic al acestor genotipuri, s-au dezvoltat astfel vaccinuri profilactice.

Vaccinurile HPV sunt extrem de eficiente în prevenirea infecţiilor şi, totodată, a neoplaziilor determinate de virus, dar nu induc efecte terapeutice împotriva acestora.

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